I have a question, I've been on Evra patches for two years, I always change the patches systematically on Fridays, it hasn't happened to me yet that I've forgotten about it. Recently I noticed that on Saturday and Friday I changed the patch and I got brown spots that lasted about two days, then they were slightly yellow. It was my 3rd patch, I would like to add that when it comes to medications that weaken the patch, at the beginning of the cycle I was sick, but I didn't take any antibiotics, regular Ibuproms, Tabcin, the only prescription drug is Rupurix, but as far as I know it doesn't weaken the effect. My question is, are such mid-cycle spotting simply undesirable actions of the patches? I had an appointment two months ago for an ultrasound and cytology and everything was fine. Is vaginal discharge on the patches normal? I'd like to add that it was on the 3rd patch, and now I had withdrawal bleeding, which normally occurred and lasted for a couple of days.