Good morning. Please inform me about the effect of the drug Ivabradine - is this drug actually stronger than verapamil? Since the passage of covid a year ago I have tachycardia - a resting heart rate of about 90 / min (at a pressure of 125/70) without medication, and during exercise or walking heart rate is over 140 which makes me tired quickly. The cardiologist performed tests: Holter, ECG, ECG, echocardial echo. In Holter it turned out that I have a tendency to sinus tachycardia. The doctor first recommended Isoptin 240 SR-E, but my heart rate only dropped to about 80 / min at rest, and the pressure dropped significantly, so I did not feel well. I can not take a beta-blocker because of asthma and side effects. So the doctor suggested an "off-label" treatment of Bixebre - ivabradine at a dose of 7.5 mg in the morning and evening, because it supposedly only lowers the pulse and more strongly than other drugs. Unfortunately, this drug is very expensive, the monthly treatment is as much as PLN 120, and I am not entitled to reimbursement, so I wonder whether to start therapy, whether this new drug will actually be more effective in reducing heart rate. Therefore, I have a question for you: 1. Is Ivabradine (7.5mg) really stronger and will lower my resting heart rate more than the current Isoptin 240 SR-E? 2. I also have doubts about the heart rate at night during sleep, because during sleep in the ECG holter, my heart rate was at the lowest moment 48 / min (taking the above mentioned Isoptin in the morning). I am afraid that at night during sleep, the heart rate will drop even more when using a new drug. Is it possible? I found an article on the Internet that it does not affect the heart rate at night significantly, but I would ask for confirmation. Thank you for your reply.