Welcome to licensed pharmacies in Poland:
Non-prescription medicines delivery across Europe.
Frequently ordered: potency boosters (sildenafil OTC), quit smoking aids.
Does Xifaxan reduce the effectiveness of Ginoring?
Good morning, does using Xifaxan reduce the effectiveness of Ginoring? On the leaflet there is information that the use of Xifaxan reduces the effectiveness of oral contraception.
* required field
* required field
Other messages will not be sent.
Klaudia Ćwiąkała Pharmacist, Editor
17 months ago
Xifaxan may affect the effectiveness of the Ginoring disc. It is usually recommended to use condoms additionally throughout the period of use of Xifaxan and for 28 days after discontinuation. Rifaximin (the active ingredient in Xifaxan) is a weak inducer of cytochrome P450 CYP3A4 isoenzyme, and ginoring disc documentation indicates that "There may be interactions with medicinal products or herbal products that induce microsomal enzymes, especially cytochrome P450 (CYP) enzymes, which may lead to an increase in clearance, resulting in a decrease in plasma sex hormones and a decrease in the effectiveness of combined hormonal contraceptives, including the Ginoring vaginal therapeutic system." I attach additional materials: https://www.gdziepolek.pl/produkty/96195/ginoring-przyrzad/ulotka https://www.gdziepolek.pl/artykuly/jakie-leki-oslabiaja-skutecznosc-antykoncepcji