is it possible to combine with each other: Mysimba, Cortiment, Euthyrox and Glucophage?

There are some interactions between the drugs mentioned in the question. Due to their nature and severity, however, in general, these interactions are not a contraindication to the simultaneous use of these drugs. However, it is worth being aware of what the effects of simultaneous use of these drugs may be, so that if they are observed, the patient can relate the symptoms with the fact of combining specific substances. Thyroid hormones (Euthyrox) and glucocorticoids (Cortiment MMX) can weaken the hypoglycaemic effect of oral antidiabetic drugs (Glucophage). Glucose levels should be monitored in patients taking this combination; especially when starting, modifying or interrupting thyroid hormone treatment. Please note that the more medications a patient takes, the greater the risk of adverse interactions between them. Already taking two drugs at the same time creates a risk of undesirable interactions at the level of 13-14%. If a patient takes 8 to 10 medications at the same time, it is almost certain that there will be interactions between them and there will be interactions that negatively affect the patient's health. This problem applies especially to the elderly, treated for several diseases at the same time. I enclose additional information that may be helpful: https://www.gdziepolek.pl/artykuly/czy-bac-sie-dzialan-niepozadanych-lekow https://www.gdziepolek.pl/artykuly/czy-mozna-laczyc-leki-ze-soba