Is Nimesil stronger than Ketonal?

Nimesil and Ketonal contain various active substances. They are characterized by similar analgesic and anti-inflammatory properties, differ in the risk of side effects. In the event that the perceived effect of the prescribed drug is too weak, it is recommended to consult the attending physician. It may be necessary to make changes to the proposed pharmacotherapy. Nimesil contains nimesulide as the active substance. The pharmacological action of nimesulide is mainly associated with the effect on inhibiting the activity of cyclooxygenase-2 (COX-2). Nimesil has only a small effect on the activity of cyclooxygenase-1 (COX-2), which significantly reduces the risk of possible side effects (such as gastrointestinal bleeding). In addition, it comprehensively inhibits the activity of other mediators of inflammation. Nimesulide is usually recommended as a second-line drug to relieve acute pain. The analgesic effect of the drug lasts about 10 hours: https://www.gdziepolek.pl/produkty/53354/nimesil-granulat-do-wytworzenia-zawiesiny/ulotka Ketonal contains ketoprofen as the active substance. The pharmacological action of ketoprofen is associated with the inhibition of the activity of cyclooxygenase-1 (COX-1), as well as cyclooxygenase-2 (COX-2). In addition, it inhibits the release of other mediators of inflammation. The effect on both cyclooxygenase isoenzymes is associated with an increased risk of drug side effects (such as gastrointestinal ulcers). In addition, ketoprofen can cause the occurrence of m.in acute renal failure. Ketonal is recommended, m.in, to relieve some of the symptoms of pain syndromes. The analgesic effect of the drug lasts about 6 - 8 hours: https://www.gdziepolek.pl/produkty/40051/ketonal-forte-tabletki-powlekane/ulotka The availability of preparations can be checked using the links: https://www.gdziepolek.pl/produkty/53354/nimesil-granulat-do-wytworzenia-zawiesiny/apteki https://www.gdziepolek.pl/produkty/40051/ketonal-forte-tabletki-powlekane/apteki To sum up, Nimesil is a more beneficial preparation due to the duration of action of the preparation, as well as the ratio of the expected benefits (analgesic and anti-inflammatory effects) to the risk (occurrence of side effects). In the event that the perceived healing effect is not enough, it is recommended to consult the attending physician. In addition, other preparations with analgesic and anti-inflammatory effects (such as ibuprofen) should not be used due to the increased risk of side effects m.in from the gastrointestinal tract. I encourage you to familiarize yourself with additional materials that may be useful: https://www.gdziepolek.pl/artykuly/jakie-leki-przeciwbolowe-stosowac https://www.gdziepolek.pl/kategorie/leki-przeciwbolowe https://www.gdziepolek.pl/kategorie/bol-zeba

Nimesil was withdrawn from some countries. I'm also wondering if I should turn it into ketonal. I have inflammation of the upper tooth 4 nothing helped even nimesil. Apap, pyralgina, ibuprom swallowed like candy no action. I go to the store or the doctor to get a ketonal and see. Only cold water compresses allow me to survive. For masters, do not use an infrared lamp in case of toothache. The pain gets worse