Good morning. I take duloxetine and aripiprazole. The psychiatrist told me to take reagilie. Is it safe to use these drugs together? Does he get fat after reacting? I would like to add that he suffers from schizophrenia. Thank you for your reply.
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Olga Sierpniowska Pharmacist, Editor
18 months ago
As for the drugs you mentioned, it is believed that duloxetine may inhibit the hepatic metabolism of aripiprazole, increase its concentration and increase the potential side effect. Cariprazine, attached to medications already in use, may increase anticholinergic effects, which means that effects such as drowsiness, blurred vision, dry mouth, heat intolerance, redness, decreased sweating, difficulty urinating, abdominal cramps, constipation, irregular heartbeat, confusion and memory problems may appear or worsen. They can - which does not mean that they have to and that they will definitely occur with you. The fact that there may be interactions between drugs does not mean that they must not be combined. Appropriate dose adjustment and careful monitoring of one doctor who knows the patient's case and self-observation of the body's response to the addition of a new drug may be enough to safely conduct therapy. Since the psychiatrist knew what drugs you were already using, the choice of Reagila was probably well thought out. The use of Reagila may cause a significant increase in body weight. This side effect may affect up to 1 in 10 people. Statistically, however, in most patients, such a side effect does not occur. I enclose information about the drug Reagila, which can be booked through GdziePoLek, and then picked up stationary after presenting a prescription: https://www.gdziepolek.pl/produkty/98044/reagila-kapsulki/apteki/w-warszawie You may also be interested in our studies: https://www.gdziepolek.pl/artykuly/jak-zyc-ze-schizofrenia https://www.gdziepolek.pl/artykuly/czy-bac-sie-dzialan-niepozadanych-lekow