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xyzzz (Anonymous, 31.61.184.) Warszawa 14 months ago

What drugs can affect the result of the PAPP-A and betaHCG tests?

What drugs can affect the poor result of the PAPP-A and betaHCG test?

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Joanna Dunajska Pharmacist, Editor

14 months ago

According to the available literature data, which I was able to find, high doses of statins, e.g. atorvastatin 80mg and drugs from the group of calcium channel antagonists may affect the reduction of PAPP-A protein concentration. Drugs that affect the concentration of betaHCG are drugs used to treat infertility, e.g. Pregnyl, Ovitrelle, because they contain chorionic gonadotropin. A small study in 23 pregnant patients demonstrated the effect of antiepileptic drugs (carbamazepine, valproic acid and lamotrigine) on the elevation of beta-HCG levels in screening tests conducted in the first trimester of pregnancy.

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