Good morning. My therapeutic dose is 200mg. For 4 days I did not use the morning doses of Lamilept (100mg) because I was away from home and had no way to take the drug. I forgot about him. In the evening I took the second 100mg normally. Now I took the morning dose after these few days (100mg) Is it safe? I contacted the pharmacist and he told me that if I took the medicine in the evening there should be no side effects associated with returning to the morning dose, but I wanted to make sure from other sources.
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Aleksandra Żywiec-Pelczar Pharmacist
17 months ago
In the situation described in the question, a gradual increase in the dose of lamotrigine contained in Lamilept is not required. Given the pharmacokinetic properties of the drug, m.in its mean half-life and the fact that the morning dose interval was 4 days, you can safely return to use the drug in the morning and evening. In patients who have completely discontinued the drug for more than a week, due to the possibility of rash, it is recommended to gradually increase the dose until the therapeutic dose is reached. In the case you described, there is no such necessity. You can read about whether, how and when you can stop taking medication in the text: https://www.gdziepolek.pl/artykuly/czy-jak-i-kiedy-mozna-odstawic-leki