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dziadek (Anonymous, 109.173.213.) Polska 16 months ago

Should I increase Candepress 8 mg to 2 tablets if my systolic blood pressure oscillates between 125-133 mmHg?
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I had the problem of hypertension under control by taking 8 mg of Candepress. For a week now, the "upper" pressure has been oscillating between 133 and 125. Do you increase Candepress to 2 x 8 mg, morning and evening? I also have - from the period of treatment for hypertension - Lecalpin 10 mg. What would be better to lower the pressure to about 125

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Angelika Talar-Śpionek

Angelika Talar-Śpionek Pharmacist, Editor

16 months ago

According to the Candepress Safety Data Sheet, it is not recommended to "split" into two doses:

'The recommended starting dose and usual maintenance dose of Candepres is 8 mg once daily. The best antihypertensive effect is achieved within 4 weeks. In patients who do not have adequate blood pressure control, the dose may be increased to 16 mg once daily and up to a maximum of 32 mg once daily."

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Angelika Talar-Śpionek

Angelika Talar-Śpionek Pharmacist, Editor

16 months ago

First, blood pressure should be measured regularly and the results recorded. Only data from at least 2 weeks can give a picture of the actual pressure values.
Most likely, it will not be necessary to increase the dose of Candepress. Nevertheless, it is a prescription drug and the final decision must be made by a doctor.

The correct values oscillate between 120 mmHg-129 mmHg. It is also worth implementing a healthy diet, regular physical activity (a walk is enough) and adequate hydration (1.5-2 liters of water a day). If the values remain above 130 mmHg, then you should consult your cardiologist.

If you are unable to consult your doctor, you can use the teleconsultation here:

https://www.gdziepolek.pl/telekonsultacja/z-kardiologiem

The pharmacist does not have the ability to modify the treatment method with prescription doctors. Here it is necessary to consult a doctor.

According to the latest ESC (European Society of Cardiology) guidelines:

"For most treated patients, the new systolic blood pressure target is between 120 mmHg and 129 mmHg, a departure from the previous two-step recommendation."

"The major change in target pressure in these guidelines is based on new data from clinical trials, which confirm that lower pressure leads to a lower incidence of cardiovascular events, resulting in a new systolic blood pressure target of 120 mmHg to 129 mmHg for the majority of patients receiving antihypertensive medications.

This systolic target represents a major change from previous European guidelines, which generally recommended that patients be treated to a target below 140/90 mmHg and only once this target is reached are treated to a target below 130/80 mmHg (two-step approach)."

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