Can pregabalin, risperidone, quetiapine and sodium valproate be used at the same time?

As long as all these drugs were prescribed by the same doctor, or the doctor prescribing subsequent drugs knew about the other medications used by the patient, there are no contraindications to their simultaneous use. This does not mean that there is no interaction between the drugs mentioned in the question. Simultaneous intake of sodium valproate (Depakine Chrono) and quetiapine (Ketrel) may be associated with m.in the risk of memory disorders, concentration, Parkinson's disease symptoms or haematological disorders. Concomitant intake of sodium valproate (Depakine Chrono), risperidone (Rispolept), quetiapine (Ketrel) and pregabalin may also cause excessive drowsiness, fatigue and difficulty in performing the intended movements. Combining quetiapine (Ketrel) and risperdine (Rispolept) may further increase the risk of hyperarousal or sedation, episodes of high fever and muscle stiffness. The symptoms of the interactions mentioned above may or may not occur. If the doctor, having knowledge of all the drugs used, has not recommended discontinuation of any of them, it may indicate that in his opinion the benefits of their use outweigh the possible risk of complications. However, you should be aware of the possibility of their occurrence so that if you observe disturbing symptoms, you can recognize them and seek specialist advice as soon as possible. https://www.gdziepolek.pl/artykuly/czy-przyjmowanie-kilku-lekow-jednoczesnie-jest-bezpieczne Below are also links to track the availability and reservation of the aforementioned drugs in the selected pharmacy: - https://www.gdziepolek.pl/produkty/67664/rispolept-tabletki-powlekane/apteki, - https://www.gdziepolek.pl/produkty/21922/depakine-chrono-300-tabletki-o-przedluzonym-uwalnianiu/apteki, - https://www.gdziepolek.pl/produkty/40080/ketrel-tabletki-powlekane/apteki, - https://www.gdziepolek.pl/produkty/89744/pregabalin-zentiva-kapsulki/apteki.