Can Trileptal and Depakine be used together for epilepsy?

There are some interactions between the medicinal substances contained in the medicinal products mentioned in the question. However, due to their nature and severity, these interactions are generally not a contraindication to the simultaneous use of these drugs. Both drugs have an antiepileptic effect. Their concomitant use may contribute to the effectiveness of treatment, but requires constant monitoring by a doctor for signs and symptoms of Depakine toxicity and adjust its dose accordingly. Trileptal may increase the concentration of Depakine and its metabolites, leading to an increase in toxicity. Trileptal was registered as the drug of first choice as monotherapy for focal onset seizures. Depakine has a wide range of action in the treatment of focal and generalized types of seizures. Depakine is still the most effective antiepileptic drug for the treatment of generalized idiopathic epilepsy with generalized tonic-clonic seizures. It should remain the drug of first choice in men with generalized epilepsy. If medicines have been prescribed by different doctors, a consultation is necessary to determine whether these medicines can be used at the same time and, if so, whether there is a need to modify the way they are taken. If the medication was prescribed by the same doctor, please follow the dosage regimen. If you experience more frequent seizures or other worrying symptoms - please contact your doctor. If you are unable to get to your primary care doctor, the GdziePoLek.pl service also allows you to obtain a teleconsultation with a doctor: https://www.gdziepolek.pl/telekonsultacja The GdziePoLek.pl service also allows you to book the drug at the nearest stationary pharmacy and pick up after presenting the prescription: Depakine Chrono 300: https://www.gdziepolek.pl/produkty/21922/depakine-chrono-300-tabletki-o-przedluzonym-uwalnianiu/apteki Trileptal: https://www.gdziepolek.pl/produkty/79923/trileptal-tolep-tabletki-powlekane/apteki