If I had intercourse during the 7-day break with contraception, and on the last day of the break until the 4th day of the active tablets of the new blister I took amoxicillin (5 days of antibiotic in total), was the intercourse during the break still protected by the protection from the previous blister? On the Internet, I find contradictory information about the reduction in the effectiveness of contraception during antibiotic therapy.
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Klaudia Ćwiąkała Pharmacist, Editor
17 months ago
Yes, if you have concerns about the effectiveness of contraception, you can use additional protection just in case.
So intercourse before taking 1 tablet of antibiotic remains protected, and from taking 1 tablet and 7 days after the end of antibiotic therapy, additional protection can be used for better safety?
Klaudia Ćwiąkała Pharmacist, Editor
17 months ago
If the previous blister was taken correctly (all active pills taken in good time), the contraceptive protection also covers the time of the break and starting antibiotic treatment during the next blister will not increase the risk of pregnancy as a result of intercourse during the break.
Contradictory information may result from the fact that opinions on the effect of antibiotics on the effectiveness of hormonal contraception are divided.
According to current scientific research, the only group of antibiotics for which a direct effect on the effectiveness of contraception has been proven are rifamycins (rifampicin, rifabutin, rifaximin). They stimulate enzymes in the liver that break down hormones contained in contraceptives (ethinylestradiol and progestogens), which reduces their concentration in the body and weakens the contraceptive effect.
Scientific studies have not confirmed the negative effect of other antibiotics, including amoxicillin, on the effectiveness of hormonal contraception. However, many experts believe that there are too few qualitative studies available to completely rule out the effect of antibiotics on the effectiveness of contraception. Therefore, it is often recommended to use an additional, barrier method of contraception (e.g. condoms) during antibiotic therapy and for 7 days after its completion. You can find more information in this article: https://www.gdziepolek.pl/artykuly/jakie-leki-oslabiaja-skutecznosc-antykoncepcji