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KATRINAA (Anonymous, 95.51.10.) Warszawa 10 months ago

Can people who are allergic to penicillins take Duracef?

I am allergic to ospamox. I used to take polopyrine S, does it contain penicillin? Now I have the antibiotic duracef, is it safe for allergy to ospamox?

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Aleksandra Żywiec-Pelczar Pharmacist

10 months ago

Polopyrin S contains acetylsalicylic acid. There is no penicillin in its composition. Ospamox contains amoxicillin, a semi-synthetic penicillin substance. Duracef contains cephalosporin cefadroxil - antibiotics. Due to the fact that amoxcicillin and cefadroxil belong to a wider group of so-called betalactam antibiotics - their chemical structure is similar, and thus, patients diagnosed with allergy to any antibiotics included in this group are more likely to experience so-called cross-reactions that may occur between penicillins and other betalactam antibiotics. However, when Duracef is used by patients allergic to Ospamox, this risk is low - hypersensitivity to cephalosporins (e.g. Duracef) is found in only 1-3% of patients with hypersensitivity to penicillins (e.g. Ospamox). Below is a link to a text that may be of interest: https://www.gdziepolek.pl/artykuly/fakty-i-mity-o-antybiotykach Use the link below to track the availability of Duracef and book online: https://www.gdziepolek.pl/produkty/25626/duracef-kapsulki/apteki

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