Why did my testosterone level decrease and estradiol levels decrease during testosterone therapy?

In order for the test results to be considered reliable, they should be carried out in the morning, before using Androtope. If you have acted in this way and the results show that the effect of the therapy is not satisfactory, you should present the result to your doctor - it may be necessary to increase the dose of the drug. As for elevated estradiol - here it is also worth consulting a doctor. It should be known that a periodic increase in estradiol concentration may accompany testosterone therapy because these hormones are actually dependent on each other. The aromatase enzyme turns testosterone into estrogen, eventually causing it to be excess. It is worth discussing the result of the examination with a doctor, because in this case taking substances aimed at increasing the amount of testosterone may not be appropriate, because it will have the opposite effect. A better treatment may be, for example, inhibiting the activity of the aromatase enzyme, thus preventing the production of an inflated amount of estrogen. In my opinion, it is necessary to visit a specialist to assess whether further testosterone therapy is the right solution in your case.