Can I take Acodin while taking Paroxetine and Mirtazapine?

No, Acodin should not be used in this case. During the simultaneous use of selective serotonin reuptake inhibitors (SSRIs) (here: Paroxetine iMirtazapine) and Acodin, there is a possibility of serotonin syndrome, probably due to the summation of the serotonergic effect. Serotonin syndrome is manifested m.in confusion, agitation, fever, sweating, ataxia, hyperreflexia, muscle clonic seizures and diarrhea. This condition is distinguished by the so-called triad of symptoms, which includes: 1. Vegetative disorders, i.e. an increase in blood pressure, fever, diarrhea, vomiting and mydriasis. 2. Psychiatric symptoms, consisting of anxiety disorders, feelings of anxiety and confusion. 3. Neuromuscular ailments, i.e. recurrent cramps, pain and increased muscle tone. In addition, Paroxetine may increase the concentration of dextromethorphan (the active substance of Acodin) in serum by inhibiting its metbolism. Therefore, if you observe this type of side effects, you should inform your doctor, who will decide on this basis about further proceedings. If you are unable to get to your primary care doctor, the gdziepolek.pl service also allows you to obtain a teleconsultation with your doctor: https://www.gdziepolek.pl/telekonsultacja