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Anna (Anonymous, 109.125.254.) Warszawa 5 months ago

Should I double my insulin dose if my doctor switches Tresiba from 200 U/mL to 100U/mL?

I was taking 18 J of insulin tresiba in a 200J pen per ml. Now I have tresibe penfil 100j per ml. Should I double the dose, i.e. take 36 J of this insulin?

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Anna Lewandowska Pharmacist, Editor

5 months ago

As a pharmacist, I can only give you general information on this, but I encourage you to consult your doctor before making any changes to your insulin dosage.

Tresiba is a long-acting human insulin analogue produced by recombinant DNA using baker's yeast, insulin degludec.
Tresiba is available in two concentrations (200 U/ml and 100 U/ml). For each concentration, the appropriate dose is set in units. The degree of dose escalation is different for both concentrations of Tresiba:

* For Tresiba 100 units/ml, the dose from 1 to 80 units per injection can be set in one-unit increments.

* For Tresiba 200 units/ml, the dose from 2 to 160 units per injection can be set in two-unit increments. The dose is half the volume of basal insulin 100 units/ml.

The dose counter indicates the number of units regardless of the concentration. Doses should not be recalculated when changing the concentration of the medicine.

If in doubt, I encourage you to consult your doctor again. It is the doctor who decides on the possible treatment of the patient, m.in. on the basis of the patient's medical history and previous response to treatment. Only the doctor can decide whether to change the pharmacotherapy. If you do not have the possibility of an in-person visit, I encourage you to take advantage of the teleconsultation, e.g. via the Gdziepolek.pl portal:

https://www.gdziepolek.pl/telekonsultacja/z-diabetologiem

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