Can Glucophage and Ozempic cause hypoglycaemia? What happens when I stop Ozempic?

In response to the great interest of patients, a non-reimbursed drug Ozempic from parallel imports appeared in pharmacies. The availability of the drug in pharmacies can be checked here: Ozempic 0.5 mg https://www.gdziepolek.pl/produkty/99258/ozempic-iniekcja/apteki?pvid=275329 Ozempic 1 mg https://www.gdziepolek.pl/produkty/99258/ozempic-iniekcja/apteki?pvid=275351

Sorry, these are not fears, but facts.

During the time of taking Mundazhro from June 2025 to December 2025 with a gradual increase in dosage from 2.5 mg to 10 mg, I experienced 5 more near-hypoglycemic states, and being already an experienced "gipper" when an attack was approaching (and it usually came 2-3 days after the injection at dosages of 5 mg and above), I managed to "remove" with a candy. Once there was no candy, and since I was quite far from the house, I had to tear my hand into blood with the keys. And then, at dosages from 7.5, strong dyspeptic effects began, both upper and lower, and pain in the right hypochondrium, which the sculptors tried to treat with pantoproazole, and only on the ultrasound in October it turned out that these were newly formed gallstones, which did not exist in February.

So don't make me think that GLP-1 doesn't make you - it HAPPENS, and I experienced it on my own skin. As for insulin levels, the therapy cost me an increase in the level of fasting insulin from 19.5 to 22.5 in six months with the same levels of sugar and glycated hemoglobin, which is DIRECT evidence that drugs of this type WORSEN THE COURSE OF INSULIN RESISTANCE.

To @ocuvalon:

No, the following statement is not true. Ozempic (semaglutide) is a drug used to treat type 2 diabetes as well as to treat obesity. Its main mechanism of action is to stimulate insulin secretion in response to elevated blood glucose levels. This means that Ozempic helps to control blood sugar levels, and does not "shake up" insulin resistance or lead directly to diabetes.

As for the pancreas, there is no evidence that Ozempic causes its destruction. On the contrary, it has been shown in clinical trials that semaglutide can protect the pancreas and improve the functions of pancreatic beta cells that produce insulin.

Of course, like any drug, Ozempic can cause side effects, and its use should be monitored by a doctor. In rare cases, it can lead to problems such as pancreatitis, but this is very rare and is not a general side effect of this drug.

I understand your concerns. Hypoglycemia, or too low blood sugar, is a serious condition that can lead to various symptoms such as tremors, sweating, dizziness, headaches and even fainting, as in this case. Typically, hypoglycemia is considered to be a glucose level below 3.9 mmol/L (70 mg/dL), although some sources indicate that this limit may be 3.5 mmol/L or slightly higher.

If you feel unwell at levels of 4.1 mmol/L and experience the classic symptoms of hypoglycaemia, it may suggest that your body reacts to sugar drops more sensitively than people without such symptoms. "Normal" glucose ranges (5.2-5.7 mmol/L) are quite typical for people with well-controlled diabetes, so the differences you notice may be related to your individual blood sugar response.

It is worth consulting again with your treating doctor, who will consider your individual needs and adjust your treatment plan, including possible changes in medication dosage or glucose monitoring. There is also a possibility that this phenomenon is due to drug interactions, such as Ozempic, which can affect the rate of insulin secretion and the body's response to changes in glucose levels.

In this situation, it may also be helpful to monitor your blood glucose throughout the day (e.g. for several days) at different times to see if your blood sugar levels are stable at other times of the day or if there are fluctuations that could explain the onset of these symptoms.

Glucophage is metformin. It's unrealistic to kick off it, because it's weak and generally useless.

Ozempic is a pancreatic killer. It additionally stimulates it to produce larger and larger doses of insulin, thereby rocking insulin resistance and bringing diabetes closer.

I went to a hypoglycemic faint on it twice with the classic symptoms in the form of a severe headache, sweating, and tremors, and both times it was relieved sweet, and the sugar level that I measured at the exit from the second fainting was 4.1 mmol/mol, with my characteristic 5.2-5.7. Doctors bury the head in the sand, claiming that hypoglycemia is below 3.5 mmol/mol, the rest is of no interest to them.