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wiki (Anonymous, 77.65.160.) Warszawa 44 days ago

Does Actrapid reduce blood glucose levels for the duration of its action?
9.99 zł

Good morning. I would like to ask you about the effect of the short-acting insulin Actrapid. I've read that the maximum effect is after 1.5-3.5 hours, but it works up to 8 hours. Does it mean that after these 3.5 to 8 hours it gradually reduces the glycemic level or only maintains it?

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Klaudia Ćwiąkała Pharmacist, Editor

44 days ago

Actrapid is a short-acting human insulin. The onset of action occurs within half an hour, the maximum effect between 1.5 and 3.5 hours, and the total duration of action is about 7-8 hours and decreases gradually. During this time, it may lower glycaemic levels.

Therefore, when administering short-acting human insulin with meals, the patient may need to snack between the main meals, i.e. e.g. when administering insulin half an hour before the first breakfast, the second breakfast should also be eaten, and when administering insulin before lunch, the patient should eat an afternoon snack. Skipping an extra meal can lead to hypoglycaemia.

I've attached a link to a helpful post:

https://www.gdziepolek.pl/kategorie/insulina-w-cukrzycy-rodzaje-dzialanie-sposoby-podawania

and the package leaflet: https://www.gdziepolek.pl/produkty/2254/actrapid-penfill-iniekcja/ulotka

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