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Chrissi (Anonymous, 41.73.203.) Warszawa 5 months ago

Can there be bleeding changes while using Zafrill? How do I take my medicine in a different time zone?

Good day
I take Zafrilla to treat suspected endometriosis. I've had spotting almost since I started taking it. What is your experience with regard to? The duration of the bleeding changes?

And what is the best way to take Zafrilla when there is a significant time difference on holiday? Do I adjust to local time or do I stick to my local time? If necessary, a nightly intake would then be necessary?? 😬

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Klaudia Ćwiąkała Pharmacist, Editor

4 months ago

You may experience changes in your bleeding profile while you are taking Zafrilla, such as spotting, irregular bleeding or amenorrhea.

The tablets should be consumed at regular intervals of about 24 hours, i.e. according to the time at home, but if it falls at a troublesome time in the local time, e.g. in the middle of the night, it is allowed to postpone the time of taking the drug by a few hours.

I'm attaching the package leaflet: https://www.gdziepolek.pl/produkty/98411/zafrilla-tabletki/ulotka

Marc (derEndoRechercher) (Anonymous, 90.186.23.) 4 months ago

Hi Chrissi,
Spotting is one of the possible side effects of Zafrilla - studies have shown that spotting can occur especially at the beginning of hormone therapy and can decrease in probability with taking it over a longer period of time.

In terms of intake, according to the package leaflet, you should stick to a fixed regular intake (every 24 hours, i.e. at your local time, even if this is not exactly pleasant at night on vacation), otherwise the hormone level can be confused and there may be an increased intake. You should discuss missing/forgotten doses, as well as overdoses of the medication and associated side effects with your doctor.

User questions and answers that provide feedback about products are not verified for the purchase or use of the product. Companies often order anonymous comments to form positive opinions about their products, or negative ones about competitors. Therefore, be guided by the information in the pharmacists' responses in the first place.

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