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Non-prescription medicines delivery across Europe.

Frequently ordered: potency boosters (sildenafil OTC), quit smoking aids.

Advencee (Anonymous, 195.140.131.) Warszawa 5 years ago

How much does the body purify after 5 days (2×20mg) of taking Isotek? The same as with a full course of treatment for several months?

How much does the body cleanse after 5 days (2×20mg) of taking Isotek? The same as with a full several months of treatment?

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Katarzyna Domagała

Katarzyna Domagała Pharmacist

5 years ago

Producent leku Izotek w Charakterystyce Produktu Leczniczego nie podaje informacji, czy czas eliminacji substancji czynnej leku oraz jej 3 metabolitów jest taki sam po 5 dniach, jak po kilkumiesięcznej kuracji.

Po podaniu doustnym izotretynoiny okres półtrwania w końcowej fazie eliminacji, czyli czas po którym stężenie leku we krwi spadnie o połowę, u pacjentów z trądzikiem wynosił średnio 19 godzin.
Okres półtrwania 4-oksoizotretynoiny (metabolitu) w końcowej fazie eliminacji jest dłuższy, wynosi średnio 29 godzin.

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